The identification of the elements, in conjunction with the knowledge of the differential regulation in a variety of tissues, offers a new system for the discovery of estrogenic medicines with SERM-like profiles.’ Related StoriesStudy shows uncommon HER2 missense mutations usually do not spread breasts cancer on the ownMD Anderson research reveals why chemotherapy medications not effective for most pancreatic cancers patientsScientists discover little molecule that may block development of BRCA-deficient cancers cellsThe study was carried out by investigators at THE GUTS for Reproductive Sciences in the Division of Obstetrics, Gynecology and Reproductive Sciences at the University of California, SAN FRANCISCO BAY AREA in collaboration with researchers at Bionovo.This is a big opportunity that may exceed $700 million worldwide. In some cases, drainage is inadequate, and the surplus liquid accumulation called seroma needs an additional process of removal. TissuGlu adheres the tissue flaps created during the procedure to reduce fluid accumulation, and, ultimately, the duration of use of the surgical drains.. Children and Consent The concept of informed consent has little direct application in children. Although minors may possess appropriate decision-making capacity, they usually do not have legal empowerment to give informed consent. Therefore, parents or various other surrogate decision-makers may give informed permission for analysis and treatment of a child, preferably with the assent of the child whenever possible. In most cases, parents are assumed to do something in the very best interest of the youngster.